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PLCB4

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4;1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4; Isoform 3 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4; Isoform 4 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4; Isoform 1 of 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4

Activated phosphatidylinositol-specific phospholipase C enzymes catalyze the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) involved in G-protein coupled receptor signaling pathways. PLCB4 is a direct effector of the endothelin receptor signaling pathway that plays an essential role in lower jaw and middle ear structures development (PubMed:35284927).

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • PLCB4

UniProt ID

  • Q15147
  • Q15147-4
  • Q15147-5
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