UPAR

Isoform 2 of Urokinase plasminogen activator surface receptor;Urokinase plasminogen activator surface receptor

Acts as a receptor for urokinase plasminogen activator (PubMed:15677461). Plays a role in localizing and promoting plasmin formation. Mediates the proteolysis-independent signal transduction activation effects of U-PA. It is subject to negative-feedback regulation by U-PA which cleaves it into an inactive form.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • PLAUR

UniProt ID

  • Q03405
  • Q03405-2

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