PDS5B

Isoform 2 of Sister chromatid cohesion protein PDS5 homolog B;Sister chromatid cohesion protein PDS5 homolog B

Regulator of sister chromatid cohesion in mitosis which may stabilize cohesin complex association with chromatin. May couple sister chromatid cohesion during mitosis to DNA replication. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Plays a role in androgen-induced proliferative arrest in prostate cells.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • PDS5B

UniProt ID

  • Q9NTI5

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