Binds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3-phosphate (By similarity). Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A (PubMed:16176980). Binds 25-hydroxycholesterol and cholesterol (PubMed:17428193).

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • OSBPL1A

UniProt ID

  • Q9BXW6

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