NUBP1

Isoform 2 of Cytosolic Fe-S cluster assembly factor NUBP1;Cytosolic Fe-S cluster assembly factor NUBP1

Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery (PubMed:18573874). Required for maturation of extramitochondrial Fe-S proteins (PubMed:18573874). The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins (PubMed:18573874). Implicated in the regulation of centrosome duplication (By similarity). Negatively regulates cilium formation and structure (By similarity).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • NUBP1

UniProt ID

  • P53384

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