5NT3B

7-methylguanosine phosphate-specific 5'-nucleotidase; Isoform 2 of 7-methylguanosine phosphate-specific 5'-nucleotidase

Specifically hydrolyzes 7-methylguanosine monophosphate (m(7)GMP) to 7-methylguanosine and inorganic phosphate (PubMed:23223233, PubMed:24603684). The specific activity for m(7)GMP may protect cells against undesired salvage of m(7)GMP and its incorporation into nucleic acids (PubMed:23223233). Also has weak activity for CMP (PubMed:23223233, PubMed:24603684). UMP and purine nucleotides are poor substrates (PubMed:23223233).

Associated with:

Nucleotide Metabolism

Matrix Type

Tissue/Cells

Gene Symbol

NT5C3B

UniProt ID

Q969T7

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5NT3B

7-methylguanosine phosphate-specific 5'-nucleotidase; Isoform 2 of 7-methylguanosine phosphate-specific 5'-nucleotidase

Associated with:

Matrix Type

Gene Symbol

UniProt ID

Request the 5NT3B Assay

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