NSUN4

Isoform 4 of 5-methylcytosine rRNA methyltransferase NSUN4;5-methylcytosine rRNA methyltransferase NSUN4

Involved in mitochondrial ribosome assembly. 5-methylcytosine rRNA methyltransferase that probably is involved in mitochondrial ribosome small subunit (SSU) maturation by methylation of mitochondrial 12S rRNA; the function is independent of MTERFD2/MTERF4 and assembled mitochondrial ribosome large subunit (LSU). Targeted to LSU by MTERFD2/MTERF4 and probably is involved in a final step in ribosome biogenesis to ensure that SSU and LSU are assembled. In vitro can methylate 16S rRNA of the LSU; the methylation is enhanced by MTERFD/MTERF4.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • NSUN4

    UniProt ID

    • Q96CB9

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