NFAC1

Nuclear factor of activated T-cells, cytoplasmic 1; Isoform 10 of Nuclear factor of activated T-cells, cytoplasmic 1; Isoform B-alpha of Nuclear factor of activated T-cells, cytoplasmic 1; Isoform B-beta of Nuclear factor of activated T-cells, cytoplasmic 1; Isoform C-beta of Nuclear factor of activated T-cells, cytoplasmic 1;Nuclear factor of activated T-cells, cytoplasmic 1

Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 or IL-4 gene transcription. Also controls gene expression in embryonic cardiac cells. Could regulate not only the activation and proliferation but also the differentiation and programmed death of T-lymphocytes as well as lymphoid and non-lymphoid cells (PubMed:10358178). Required for osteoclastogenesis and regulates many genes important for osteoclast differentiation and function (By similarity).

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • NFATC1

UniProt ID

  • O95644
  • O95644-4
  • O95644-5
  • O95644-6

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