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NECA3

N-terminal EF-hand calcium-binding protein 3; Isoform 3 of N-terminal EF-hand calcium-binding protein 3; Isoform 1 of N-terminal EF-hand calcium-binding protein 3

Inhibits the interaction of APBA2 with amyloid-beta precursor protein (APP), and hence allows formation of amyloid-beta. May enhance the activity of HIF1A and thus promote glycolysis under normoxic conditions; the function requires its ABM domain and may implicate the stabilization of the interaction between HIF1AN and APBA3.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • NECAB3

    UniProt ID

    • Q96P71
    • Q96P71-3
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