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MON1A

Isoform 4 of Vacuolar fusion protein MON1 homolog A; Isoform 2 of Vacuolar fusion protein MON1 homolog A; Isoform 5 of Vacuolar fusion protein MON1 homolog A; Isoform 3 of Vacuolar fusion protein MON1 homolog A;Vacuolar fusion protein MON1 homolog A

Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form (PubMed:23084991).

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • MON1A

    UniProt ID

    • Q86VX9
    • Q86VX9-3
    • Q86VX9-4
    • Q86VX9-5
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