MKS1

Isoform 2 of Tectonic-like complex member MKS1;Tectonic-like complex member MKS1

Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Involved in centrosome migration to the apical cell surface during early ciliogenesis. Required for ciliary structure and function, including a role in regulating length and appropriate number through modulating centrosome duplication. Required for cell branching morphology.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • MKS1

UniProt ID

  • Q9NXB0

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