M3K1

Mitogen-activated protein kinase kinase kinase 1

Component of a protein kinase signal transduction cascade (PubMed:9808624). Activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4 (PubMed:9808624). May phosphorylate the MAPK8/JNK1 kinase (PubMed:17761173). Activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway (PubMed:9808624).

Associated with:

KRAS Signaling
MAPK Cascade
Hypoxia
Protein Phosphorylation

Matrix Type

Tissue/Cells

Gene Symbol

MAP3K1

UniProt ID

Q13233

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M3K1

Mitogen-activated protein kinase kinase kinase 1

Associated with:

Matrix Type

Gene Symbol

UniProt ID

Request the M3K1 Assay

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