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LRCH4

Leucine-rich repeat and calponin homology domain-containing protein 4

Accessory protein that regulates signaling by multiple TLRs, acting as a broad-spanning regulator of the innate immune response. In macrophages, binds LPS and promotes proper docking of LPS in lipid raft membrane. May be required for lipid raft maintenance.

Associated with:

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • LRCH4

UniProt ID

  • O75427
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