Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity.

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • KALRN

UniProt ID

  • O60229

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