HMGA1

Isoform HMG-Y of High mobility group protein HMG-I/HMG-Y;High mobility group protein HMG-I/HMG-Y

HMG-I/Y bind preferentially to the minor groove of A+T rich regions in double-stranded DNA. It is suggested that these proteins could function in nucleosome phasing and in the 3′-end processing of mRNA transcripts. They are also involved in the transcription regulation of genes containing, or in close proximity to A+T-rich regions.

Matrix Type

  • Tissue/Cells

Gene Symbol

  • HMGA1

UniProt ID

  • P17096
  • P17096-2

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