GFPT1

Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1; Isoform 2 of Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1;Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1

Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins. Regulates the circadian expression of clock genes BMAL1 and CRY1 (By similarity). Has a role in fine tuning the metabolic fluctuations of cytosolic UDP-GlcNAc and its effects on hyaluronan synthesis that occur during tissue remodeling (PubMed:26887390).

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • GFPT1

UniProt ID

  • Q06210

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