FRM4B

Isoform 2 of FERM domain-containing protein 4B;FERM domain-containing protein 4B;FERM domain-containing protein 4B

Member of GRP1 signaling complexes that are acutely recruited to plasma membrane ruffles in response to insulin receptor signaling. May function as a scaffolding protein that regulates epithelial cell polarity by connecting ARF6 activation with the PAR3 complex. Plays a redundant role with FRMD4A in epithelial polarization.

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • FRMD4B

UniProt ID

  • Q9Y2L6

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