DUSTY

Dual serine/threonine and tyrosine protein kinase; Isoform 2 of Dual serine/threonine and tyrosine protein kinase

Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation (PubMed:23862974, PubMed:28157540). Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death (PubMed:15178406). In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types (PubMed:28157540).

Matrix Type

  • Tissue/Cells

Gene Symbol

  • DSTYK

UniProt ID

  • Q6XUX3

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