Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

Matrix Type

  • Plasma
  • Tissue/Cells

Gene Symbol

  • DOCK2

UniProt ID

  • Q92608

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