AEN

Isoform 2 of Apoptosis-enhancing nuclease;Apoptosis-enhancing nuclease

Exonuclease with activity against single- and double-stranded DNA and RNA. Mediates p53-induced apoptosis. When induced by p53 following DNA damage, digests double-stranded DNA to form single-stranded DNA and amplifies DNA damage signals, leading to enhancement of apoptosis.

Associated with:

P53 Pathway

Matrix Type

Tissue/Cells

Gene Symbol

UniProt ID

Q8WTP8

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AEN

Isoform 2 of Apoptosis-enhancing nuclease;Apoptosis-enhancing nuclease

Associated with:

Matrix Type

Gene Symbol

UniProt ID

Request the AEN Assay

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