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AGRE2

Isoform 4 of Adhesion G protein-coupled receptor E2; Isoform 5 of Adhesion G protein-coupled receptor E2;Adhesion G protein-coupled receptor E2; Isoform 3 of Adhesion G protein-coupled receptor E2; Isoform 6 of Adhesion G protein-coupled receptor E2

Cell surface receptor that binds to the chondroitin sulfate moiety of glycosaminoglycan chains and promotes cell attachment. Promotes granulocyte chemotaxis, degranulation and adhesion. In macrophages, promotes the release of inflammatory cytokines, including IL8 and TNF. Signals probably through G-proteins. Is a regulator of mast cell degranulation (PubMed:26841242).

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • ADGRE2

UniProt ID

  • Q9UHX3
  • Q9UHX3-4
  • Q9UHX3-5
  • Q9UHX3-6
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