Probable ATP-binding RNA helicase required during spermatogenesis to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Acts via the piRNA metabolic process, which mediates the repression of transposable elements during meiosis by forming complexes composed of piRNAs and Piwi proteins and governs the methylation and subsequent repression of transposons. Involved in the secondary piRNAs metabolic process. Acts via the PET complex, a multiprotein complex required during the secondary piRNAs metabolic process for the PIWIL2 slicing-triggered loading of PIWIL4 piRNAs.

    Matrix Type

    • Plasma

    Gene Symbol

    • TDRD12

    UniProt ID

    • Q587J7

    Request the TDR12 Assay

    Tell us a little more about your study so we can optimize the assay for your specific needs.

    "*" indicates required fields

    This field is for validation purposes and should be left unchanged.