Isoform 2 of Apoptosis regulatory protein Siva;Apoptosis regulatory protein Siva

Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl-x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. {ECO:0000269|PubMed:12011449, ECO:0000269|PubMed:14739602, ECO:0000269|PubMed:15034012, ECO:0000269|PubMed:15958577, ECO:0000269|PubMed:16491128}.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • SIVA1

    UniProt ID

    • O15304

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