Isoform 3 of SAM domain-containing protein SAMSN-1;SAM domain-containing protein SAMSN-1

Negative regulator of B-cell activation. Down-regulates cell proliferation (in vitro). Promotes RAC1-dependent membrane ruffle formation and reorganization of the actin cytoskeleton. Regulates cell spreading and cell polarization. Stimulates HDAC1 activity. Regulates LYN activity by modulating its tyrosine phosphorylation (By similarity). {ECO:0000250, ECO:0000269|PubMed:15381729}.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • SAMSN1

    UniProt ID

    • Q9NSI8

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