Isoform 2 of Nucleotide sugar transporter SLC35B4; Isoform 3 of Nucleotide sugar transporter SLC35B4;Nucleotide sugar transporter SLC35B4

Antiporter that transports nucleotide sugars across the endoplasmic reticulum (ER) membrane in exchange for another nucleotide sugar. May couple UDP-alpha-D-glucuronate (UDP-GlcA) or UDP-alpha-D-xylose (UDP-Xyl) efflux to UDP-alpha-D-glucuronate (UDP-GlcA) influx into the ER lumen, which in turn stimulates glucuronidation and excretion of endobiotics and xenobiotics. {ECO:0000269|PubMed:16965264, ECO:0000305|PubMed:15911612}.; [Isoform 1]: Has UDP-GlcA:UDP-GlcNAc antiporter activity. {ECO:0000269|PubMed:16965264}.; [Isoform 2]: Has UDP-GlcA:UDP-GlcNAc antiporter activity. {ECO:0000269|PubMed:16965264}.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • SLC35B4

    UniProt ID

    • Q969S0
    • Q969S0-3

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