Regulates ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Does not exhibit any protease activity on its own.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • RHBDF1

    UniProt ID

    • Q96CC6
    Off-the-shelf

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