Upon bacterial lipopolysaccharide stimulation, mediates clathrin-dependent internalization of TLR4 in dendritic cells, resulting in activation of TICAM1-mediated signaling and subsequent IFNB1 production. May regulate B-cell antigen receptor-mediated signaling. {ECO:0000250|UniProtKB:Q8CHX7}.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • RFTN2

    UniProt ID

    • Q52LD8
    Off-the-shelf

    Request the RFTN2 Assay

    Tell us a little more about your study so we can optimize the assay for your specific needs.

    "*" indicates required fields

    This field is for validation purposes and should be left unchanged.