Isoform 2 of Polypyrimidine tract-binding protein 2;Polypyrimidine tract-binding protein 2

RNA-binding protein which binds to intronic polypyrimidine tracts and mediates negative regulation of exons splicing. May antagonize in a tissue-specific manner the ability of NOVA1 to activate exon selection. In addition to its function in pre-mRNA splicing, plays also a role in the regulation of translation. ; [Isoform 5]: Reduced affinity for RNA.

Associated with:

Matrix Type

  • Tissue/Cells

Gene Symbol

  • PTBP2

UniProt ID

  • Q9UKA9

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