JUPI2

Jupiter microtubule associated homolog 2; Isoform 3 of Jupiter microtubule associated homolog 2;Jupiter microtubule associated homolog 2;Isoform 2 of Jupiter microtubule associated homolog 2

Nicotinic acid adenine dinucleotide phosphate (NAADP) binding protein required for NAADP-evoked intracellular calcium release (PubMed:33758061, PubMed:33758062). Confers NAADP-sensitivity to the two pore channels (TPCs) complex (PubMed:33758061). Enables NAADP to activate Ca(2+) release from the endoplasmic reticulum through ryanodine receptors (PubMed:33758062). ; (Microbial infection) Involved in the endolysosomal trafficking of human coronavirus SARS-CoV-2.

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • JPT2

    UniProt ID

    • Q9H910
    • Q9H910-2

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