Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • IRF2BP1

    UniProt ID

    • Q8IU81

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