Plays a crucial role in the structural integrity of mitotic centrosomes and in the maintenance of spindle bipolarity by promoting PLK1 activity at the spindle poles in early mitosis. May function as a scaffold promoting the interaction between AURKA and PLK1, thereby enhancing AURKA-mediated PLK1 phosphorylation.

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • FRY

    UniProt ID

    • Q5TBA9

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