DEN4C

DENN domain-containing protein 4C;DENN domain-containing protein 4C; Isoform 3 of DENN domain-containing protein 4C;Isoform 2 of DENN domain-containing protein 4C

Guanine nucleotide exchange factor (GEF) activating RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound RAB10 into its active GTP-bound form. Thereby, stimulates SLC2A4/GLUT4 glucose transporter-enriched vesicles delivery to the plasma membrane in response to insulin.

    Matrix Type

    • Plasma
    • Tissue/Cells

    Gene Symbol

    • DENND4C

    UniProt ID

    • Q5VZ89
    • Q5VZ89-7

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