CABIN

Isoform 2 of Calcineurin-binding protein cabin-1;Calcineurin-binding protein cabin-1

May be required for replication-independent chromatin assembly. May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Acts as a negative regulator of p53/TP53 by keeping p53 in an inactive state on chromatin at promoters of a subset of it’s target genes.

    Matrix Type

    • Tissue/Cells

    Gene Symbol

    • CABIN1

    UniProt ID

    • Q9Y6J0

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