Resource Library
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Media
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Video
Experts On... Multi-Omics Data Integration
Having a multidisciplinary team gives us deep & diverse expertise to tap across our discovery endeavors.
Event
Translational Biomarkers Presentation at SLAS
March 1, 2023 | 1:00-1:30pm PT | San Diego Convention Center, Room…
Video
Experts On... Machine Learning in Biomarker Discovery
Having a multidisciplinary team gives us deep & diverse expertise to tap across our discovery endeavors.
Webinar
The Clinical Trial Conundrum: Identifying Responders vs. Non-Responders
Now On Demand | Hosted by AAPS Will a patient respond or not respond to the…
Video
Experts On... Approaching Experimental Design
Having a multidisciplinary team gives us deep & diverse expertise to tap across our discovery endeavors.
Event
Join us at Biomarkers UK
February 27-28, 2023 | Manchester Central Convention Complex Sapient will be attending Europe’s flagship event…
Article
Thinking outside the brain to advance CNS drug development
CNS diseases can have a wide range of symptoms which can make them difficult to diagnose and treat based on…
Video
Experts On... Defining Biocomputational Approaches
Having a multidisciplinary team gives us deep & diverse expertise to tap across our discovery endeavors.
Brochure
Sapient Fact Sheet
At Sapient, we believe that drugs can be developed much faster, cheaper, and more effectively through biomarker-driven drug discovery. Biomarkers…
Infographic
Chemistries & Methods: How We Achieve Breadth and Depth in Chemical Discovery
There are tens of thousands of unknown molecules circulating in human blood – thousands of which could represent robust biomarkers.
Brochure
Human Biology Database to Amplify Biomarker Discovery & Accelerate Validation
Greater discovery is enabled when data from individual disease and cohort studies can be homogenized and linked together, revealing biological…
Brochure
Fact Sheet: Analytical Methods from Discovery to Diagnostic Development
There are tens of thousands of unmapped molecules circulating in human blood – thousands of which could represent robust biomarkers.
Webinar
Fierce Webinar: Population-Scale Circulating Biomarker Discovery to Accelerate Drug Development
Now On Demand | Hosted by Fierce Pharma…
Video
"Live from the Lab" at Sapient: On-Demand Virtual Lab Tour with Bruker
Watch the Livestream Recording | Presented by Bruker Watch the full recording of our recent lab…
Article
Be More Specific: Solving the Specificity Challenge in Metabolomics
Disease processes are complex. Individuals with the same genetic disorder, symptoms, and/or diagnosis can have varied prognosis and response to…
Video
Advances in Proteomics & Metabolomics 2022 Online Symposium
Now On Demand | Presented by Technology Networks…
Podcast
SLAS New Matter Podcast: A Conversation on Small Molecule Biomarkers with Dr. Mo Jain
SLAS Scientific Manager Hannah Rosen, PhD is joined by Sapient Founder and CEO Mo Jain, MD, PhD, for an insightful discussion on small…
Webinar
What's Next in Precision Medicine? Small Molecule Biomarkers to Personalize Disease Prediction, Diagnostics and Therapies
Now On Demand | Hosted by AAPS WATCH…
Article
Fierce Pharma Feature: Small molecule biomarkers to align patients, disease, and therapy
Sapient recently contributed a piece to Fierce Pharma discussing the new biological and disease insights that small molecule biomarkers can…
Press Release
University of Oxford Publishes Findings from Its INTERBIO-21st Study Supported by Sapient’s Discovery Metabolomics
September 1, 2022—San Diego, CA—A study led by researchers at the University of Oxford, UK has been published in…
Media
Sapient Featured as Collaborator in Cedars-Sinai Study on Immune Responses and COVID-19
Study infrastructure and biospecimen processing support is being provided by Sapient for the study, which is focused on advancing vital…
Webinar
Mapping the Missing Link: Bridging the Gap Between Human Genetics and Disease Biology Through Small Molecule Biomarker Discovery
Now On Demand | Hosted by AAPS WATCH…
Press Release
Sapient Receives $9.2M Grant for Population-Scale Discovery Mass Spectrometry Analysis
The grant from Bill & Melinda Gates Foundation will support studies to identify biomarkers that can…
Article
Mapping Metabolic Changes for Diabetes Prediction with Machine Learning
Understanding the risk factors that give rise to human disease is essential to early detection and development of effective treatments…
Video
Genomic + Small Molecule Biomarkers: for a More Complete Picture of Disease Risk
An individual’s phenotype is not dictated solely by their genetic variants. Environmental factors – where we live, what we…
Media
Sapient Featured in Bruker Press Release Announcing timsTOF Innovations at ASMS 2022
“Sapient’s proprietary, next-generation rapid LC-MS (rLC-MS) technologies leverage the unique bioanalytical capabilities of the Bruker timsTOF Pro 2 system…
Article
Data ≠ Insight: Improving Metabolomics Data Interpretation
Untargeted biomarker discovery aims to uncover previously unknown factors that associate with biologically relevant changes in human health and disease,…
Webinar
Identifying Non-Invasive Biomarkers of Target Engagement
Now On Demand | Hosted by AAPS WATCH…
Article
On the Mark? Identifying Biomarkers of Target Engagement
Retrospective analyses conducted by major pharmaceutical companies on their drug pipelines have revealed that close to…
Infographic
What is Discovery at Scale? Multiplying the Rate of Nontargeted Biomarker Profiling
A drug candidate with an associated biomarker is 2−10x more likely to obtain FDA approval. Why? Because biomarkers help to…
Webinar
Smaller, Faster & More Effective: Clinical Trial Enrichment Using Circulating Biomarkers
Now On Demand | Hosted by AAPS WATCH…
Brochure
Harnessing the Human Microbiome for Discovery
The composition and function of the human gut microbiome are linked to health and disease. Increasing evidence of gut microbes’…
Press Release
Sapient Joins the Foundation for the National Institutes of Health Biomarkers Consortium
San Diego, CA—Sapient, a biomarker discovery organization transforming drug development through rapid, large-scale biomarker profiling, has joined the Foundation for…
Article
Comparison of Omics Techniques and Biomarker Types
High throughput technologies can now capture and measure a huge number of biological molecules within a single human cell or…
Case Study
Discovery of Biomarker to Predict Immunotherapy Related Autoimmunity
Immunotherapy has transformed the treatment of solid organ cancers, rapidly becoming a first line therapy with transformative durable response. While…
Overview
Untargeted Metabolomics Services for an Unprecedented Scale of Biomarker Discovery
Sapient leverages its next-generation mass spectrometry approaches to probe deeper into the human metabolome at a rate is unmatched…
Press Release
Sapient’s Diagnostic Collaboration with Bay Area Lyme Foundation Featured in the Foundation’s Annual Impact Update Report
San Diego, CA—Sapient, a full-service bioanalytical organization transforming drug development through biomarker discovery, has been featured in the Bay Area…
Video
Platform Explainer: How Sapient Accelerates Biomarker Discovery
At Sapient, we believe biomarker-driven drug development can transform lives – and accelerate the process at a fraction of…
Article
Biomarker-Driven Clinical Trials: Enriched with Biology, Evolved for a New Era
Why are large, expensive clinical trials so common? It stems from the challenge of needing to demonstrate treatment efficacy in…
Press Release
Philip Worboys, Ph.D. Joins Sapient as Head of Translational Science
San Diego, CA—Sapient, a full-service bioanalytical research organization transforming the efficiency of biomarker discovery for pharmaceutical and biotechnology sponsors, announced…
Webinar
Large Scale Biomarker Discovery: Next-Gen Mass Spectrometry Profiling to Accelerate Drug Development
Now On Demand | Hosted by AAPS WATCH…
Article
Getting Drug Development Right
The omics revolution has enabled many breakthroughs in our understanding of disease biology, but the productivity of clinical drug development…
Brochure
Circulating Biomarker Discovery at Unprecedented Speed & Scale
Did you know that underlying risks for most common human diseases are not encoded in DNA sequence? Rather, they are…
Paper
Deep Neural Networks for Classification of LC-MS Spectral Peaks
Nontargeted LC-MS can assay thousands of chemical entities in a single biospecimen, but in that crush of data, how do…
