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Webinar
Mapping the Missing Link: Bridging the Gap Between Human Genetics and Disease Biology Through Small Molecule Biomarker Discovery
Now On Demand | Hosted by AAPS WATCH…
Press Release
Sapient Receives $9.2M Grant for Population-Scale Discovery Mass Spectrometry Analysis
The grant from Bill & Melinda Gates Foundation will support studies to identify biomarkers that can…
Article
Mapping Metabolic Changes for Diabetes Prediction with Machine Learning
Understanding the risk factors that give rise to human disease is essential to early detection and development of effective treatments…
Video
Genomic + Small Molecule Biomarkers: for a More Complete Picture of Disease Risk
An individual’s phenotype is not dictated solely by their genetic variants. Environmental factors – where we live, what we…
Media
Sapient Featured in Bruker Press Release Announcing timsTOF Innovations at ASMS 2022
“Sapient’s proprietary, next-generation rapid LC-MS (rLC-MS) technologies leverage the unique bioanalytical capabilities of the Bruker timsTOF Pro 2 system…
Article
Data ≠ Insight: Improving Metabolomics Data Interpretation
Untargeted biomarker discovery aims to uncover previously unknown factors that associate with biologically relevant changes in human health and disease,…
Webinar
Identifying Non-Invasive Biomarkers of Target Engagement
Now On Demand | Hosted by AAPS WATCH…
Brochure
Human Biology Database for Population-Based Discovery
Greater discovery is enabled when data from individual disease and cohort studies can be homogenized and linked together, revealing biological…
Article
On the Mark? Identifying Biomarkers of Target Engagement
Retrospective analyses conducted by major pharmaceutical companies on their drug pipelines have revealed that close to…
Infographic
What is Discovery at Scale? Multiplying the Rate of Nontargeted Biomarker Profiling
A drug candidate with an associated biomarker is 2−10x more likely to obtain FDA approval. Why? Because biomarkers help to…
Webinar
Smaller, Faster & More Effective: Clinical Trial Enrichment Using Circulating Biomarkers
Now On Demand | Hosted by AAPS WATCH…
Brochure
Harnessing the Human Microbiome for Discovery
The composition and function of the human gut microbiome are linked to health and disease. Increasing evidence of gut microbes’…
Press Release
Sapient Joins the Foundation for the National Institutes of Health Biomarkers Consortium
San Diego, CA—Sapient, a biomarker discovery organization transforming drug development through rapid, large-scale biomarker profiling, has joined the Foundation for…
Article
Comparison of Omics Techniques and Biomarker Types
High throughput technologies can now capture and measure a huge number of biological molecules within a single human cell or…
Case Study
Discovery of Biomarker to Predict Immunotherapy Related Autoimmunity
Immunotherapy has transformed the treatment of solid organ cancers, rapidly becoming a first line therapy with transformative durable response. While…
Press Release
Sapient’s Diagnostic Collaboration with Bay Area Lyme Foundation Featured in the Foundation’s Annual Impact Update Report
San Diego, CA—Sapient, a full-service bioanalytical organization transforming drug development through biomarker discovery, has been featured in the Bay Area…
Brochure
Sapient Fact Sheet
At Sapient, we believe that drugs can be developed much faster, cheaper and more effectively through biomarker-driven drug discovery. Biomarkers…
Video
Platform Explainer: How Sapient Accelerates Biomarker Discovery
At Sapient, we believe biomarker-driven drug development can transform lives – and accelerate the process at a fraction of…
Article
Biomarker-Driven Clinical Trials: Enriched with Biology, Evolved for a New Era
Why are large, expensive clinical trials so common? It stems from the challenge of needing to demonstrate treatment efficacy in…
Press Release
Philip Worboys, Ph.D. Joins Sapient as Head of Translational Science
San Diego, CA—Sapient, a full-service bioanalytical research organization transforming the efficiency of biomarker discovery for pharmaceutical and biotechnology sponsors, announced…
Webinar
Large-Scale Mass Spectrometry Profiling: Accelerated Biomarker Discovery to Drive Drug Development
Now On Demand | Hosted by AAPS WATCH…
Article
Getting Drug Development Right
The omics revolution has enabled many breakthroughs in our understanding of disease biology, but the productivity of clinical drug development…
Brochure
Circulating Biomarker Discovery at Unprecedented Speed & Scale
Did you know that underlying risks for most common human diseases are not encoded in DNA sequence? Rather, they are…
Paper
Deep Neural Networks for Classification of LC-MS Spectral Peaks
Nontargeted LC-MS can assay thousands of chemical entities in a single biospecimen, but in that crush of data, how do…
