Greater discovery is enabled when data from individual disease and cohort studies can be homogenized and linked together, revealing biological commonalities and differences across diverse populations and diseases.

Sapient has built an expansive Human Biology Database for this purpose, comprised of data from hundreds of thousand of biosamples from individuals and studies around the world. The samples have been assayed using our rapid liquid chromatography-mass spectromerty (rLC-MS) platform for untargeted small molecule biomarker discovery, measuring over 11,000 circulating factors in each sample.

human biology database

Download this fact sheet to learn more about the database – which includes disease-centric data for more than 60 diseases and disorders, linked with longitudinal information on individuals that have been clinically followed for a range of 10-30 years – and how it can be mined to rapidly identify and validate novel biomarker discoveries.

Human Biology Database for Population-Based Discovery

Greater discovery is enabled when data from individual disease and cohort studies can be homogenized and linked together, revealing biological commonalities and differences across diverse populations and diseases. Sapient has built an expansive Human Biology Database for this purpose, comprised of data from hundreds of thousand of biosamples from individuals… Read More

Harnessing the Human Microbiome for Discovery

The composition and function of the human gut microbiome are linked to health and disease. Increasing evidence of gut microbes’ involvement in disease development has driven efforts to better understand the molecular mechanisms of pathogenesis from gut microbiota perturbation, to identify novel targets for therapeutic development. This requires comprehensive profiling… Read More

Sapient Fact Sheet

At Sapient, we believe that drugs can be developed much faster, cheaper and more effectively through biomarker-driven drug discovery. Biomarkers allow us to better align the right patient with the right disease biology and ultimately the right therapy – and this alignment is what allows for faster and more efficient… Read More

Circulating Biomarker Discovery at Unprecedented Speed & Scale

Did you know that underlying risks for most common human diseases are not encoded in DNA sequence? Rather, they are revealed in circulating chemistry stemming from human exposures including diet, toxicants, internal organs, medications, and the environment. Learn how Sapient’s transformative platform can be used for untargeted biomarker discovery and… Read More