Discovery, Untargeted Lipidomics Analysis

Amplify your lipidomics research with nontargeted profiling of the lipidome, driving rapid lipid biomarker discovery and new understanding of lipid function.

As a provider of bespoke services for the discovery of dynamic biomarkers, Sapient leverages its high throughput, untargeted lipidomics and metabolomics approaches to probe deeper into the human lipidome and metabolome at a rate is unmatched for discovery. Our mass spectrometry-based lipidomics methods lead the market in speed and scalability, enabling us to rapidly uncover both known and unknown lipid biomarkers that associate with early disease, disease progression, and drug response.

By pairing nontargeted data generation with advanced lipidomics data analysis, including lipidomics pathway analysis, we help identify robust biomarkers to elucidate lipid function and disease biology, enrich clinical trials, and align patients, disease, and precision therapies. How does it work?

  • Rapid liquid chromatography-mass spectrometry (rLC-MS) – our proprietary systems enable ultra high throughput, population-level metabolomics and lipidomics analysis in one run, measuring >15K small molecule biomarkers (metabolites and lipids) per sample, in <1 minute analytical cycle time.
  • Biocomputational integration – our expert team of data scientists perform statistical analysis of lipidomics data using machine learning tools to rapidly identify key biomarkers of interest, integrating our spectral data with other high dimensional data from preclinical models, genomics, proteomics, and clinical studies.
  • Human Biology Database – this repository is comprised of spectral data from 100,000+ human biosamples, paired with deep phenotypic information and longitudinal outcomes. Therefore, biomarkers identified through our lipidomics research studies can be cross-validated in large, independent populations.

Learn more about why Sapient is the choice lipidomics lab for novel biomarker discovery, and how we can work together to advance your drug programs at any phase. Use the sidebar to download additional details or request services directly.

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See the breadth of chemistries captured across 15K+ molecules, including polar metabolites and polar and nonpolar lipids.

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You can schedule a meeting  to discuss details and turnaround time using the link below.